A Simple Approach to Retrosynthesis in Organic Chemistry

Organic Chemistry Retrosynthesis Tutorial by Leah4sci

In Organic Chemistry, synthesis and retrosynthesis go hand in hand. While there isn’t a clear distinction, I like to think of synthesis as forward thinking and retrosynthesis as the reverse. Synthesis is a topic that is typically introduced in Organic Chemistry 1, right after studying alkyne reactions. You’ll be utilizing it again and again as […]

Choosing SN1 SN2 E1 E2 Reaction Mechanism

sn1-sn2-e1-e2-mechanism-step-by-step-video-tutorial-by-leah4sci-for-organic-chemistry-students

This video provides a step by step walk through of a difficult SN1 SN2 E1 E2 mechanism when given a product. This question comes from a student’s practice exam where over 100 students failed to get full credit. You can learn how to ace questions like this by paying attention to the LOGIC more than just […]

How to Tackle Organic Chemistry Synthesis Questions

How to tackle organic chemistry synthesis

Organic chemistry may cover many concepts and topics, but it’s all about the reactions and mechanisms. It’s not so scary at first, think about the simple acid/base deprotonation, an alkene reaction here, another there. Before you know it, you’re drowning in dozens upon dozens of reactions! You’re asked to ‘memorize’ each one, to know what every […]

Markovnikov vs Anti-Markovnikov in Alkene Addition Reactions

Markovnikov vs Anti-Markovnikov in Alkene Addition Reactions Tutorial by Leah4Sci for Organic Chemistry studentsv

Markovnikov’s Rule is a very important pattern to both understand and recognize when studying alkene addition reactions. What is Markovnikov’s rule all about and how does this impact regioselectivity in electrophilic addition reactions? As you follow along with my alkene reactions cheat sheet, you’ll notice that many reactions are labeled Mark or Anti-Mark and syn or […]

SN1 SN2 E1 E2 Reaction Mechanism Review

SN1 SN2 E1 E2 Reaction Mechanism Overview Video

SN1 SN2 E1 Series: Video 2 SN1 SN2 E1 E2 comprise the most difficult set of reactions you’ll learn in organic chemistry. The reactions themselves are simple enough but choosing which ones to use when can be tricky. This video will give you a quick overview/review of the individual reactions and mechanisms to prepare you […]

Cyclohexane Chair to Double Newman Quiz Challenge Question

Cyclohexane Chair to Double Newman Projection tutorial video

This video walks you through the Chair Conformations Practice Quiz bonus question B – Converting a cyclohexane chair conformation to double Newman Projections. Practice is ESSENTIAL to mastering Organic Chemistry. You have to be able to apply the skills you are learning. First, complete the Cyclohexane Chair Conformations Practice Quiz, and then watch this video where I go over the Challenge Question […]

Carbocation Stability and Ranking

Carbocation Stability and Ranking Tutorial by Leah4Sci

Carbocations arise so frequently in Organic Chemistry that recognizing them must become second nature. After reading this tutorial, you should be able to eyeball a molecule and determine where a carbocation is likely to form as well as its potential stability. This will help you master carbocation intermediate reactions down the line including Markovnikov alkene addition […]

Resonance Structures of Benzene

Benzene Resonance step by step in Video Tutorial Series by leah4sci

Benzene is a unique molecule when it comes to resonance structures. This video will show you how to draw the ‘circle’ of resonance for benzene, as well as resonance intermediates for substituted aromatic compounds including Electron Donating Groups EDG which resonate into the ring and Electron Withdrawing Groups EWG which cause resonance out of the ring. […]

Cyclohexane Chair Conformations Practice Quiz

Cyclohexane Chair Conformations Quiz

Chair conformations can present quite the challenge in Organic Chemistry. But they don’t have to. Start by gaining your foundation in the Chair Conformations Tutorial Series.  Then test your knowledge and understanding of this topic with the quiz below. Scroll to the very bottom of this quiz for a link to the FREE quiz solutions PDF […]

Cyclohexane Chair Conformations Axial and Equatorial Stability

Cyclohexane Chair Conformations video tutorial drawn and shown on model kit .jpg

“Why does cyclohexane have to be in a chair conformation? How do I know which carbon goes up or down?” Learn this and more in video 1 of the chair conformation series. Learn how to recognize a chair, what it represents (with a model kit and on paper) and the nature of axial and equatorial substituents. (Watch […]