Chirality and Stereochemistry R S Enantiomers Diastereomers Meso Tutorial Series

Chirality Stereochemistry Cheat Sheet

Chirality Stereochemistry Cheat Sheet

Chirality and Stereochemistry R S Enantiomers Diastereomers Meso Tutorial SeriesUnderstanding chirality is important, not only to organic chemistry, but to understand the world around you in general. I like to think of chirality as ‘handedness’.

We have a right and left hand that are similar to each other, mirror images in fact. Yet our hands are not superimposable. A right glove will not fit a left hand due to the opposite ‘handedness’.
As you work through this series, pause and try each question and make sure you’ve mastered a topic before moving on.

Download my free Stereochemistry Cheat Sheet to follow along, and be sure to try the Stereochemistry Practice Quiz once you feel ready.

Video 1 – Introduction to Stereochemistry, Enantiomers and Chiral Molecules

Introduction to stereochemsitry enantiomers and chiral molecules by Leah4sciLet’s start at the very beginning. WHAT is chirality? What does it mean for molecules? How can you identify a chiral carbon and what does that mean for its non-superimposable mirror image? All of this and more in video 1


Video 2 – R and S Configurations using Cahn-Ingold-Prelog rules

R and S Configuration Cahn Ingold Prelog rules for ranking by Leah FischNow that you understand about chirality, how do you find it’s absolute configuration to see if it’s R or S? Learn how to rank substituents using the Cahn-Ingold-Prelog system and using priorities to differentiate between R and S stereoisomers. This and more in video 2

Video 3 – Finding R and S When Group 4 is Forward

stereochemistry finding r and s when group 4 is forwardFinding R and S is easiest when priority group #4 is towards the back. But how do you find if a molecule is R or S when group #4 is facing forward? More importantly WITHOTU having to visualize a confusing 3-dimensional molecule? Learn how to use my ‘think backwards method’ and how I learned this in the military by watching video 3 (coming late october)

Video 4 – Swap Method For Finding R&S Configurations
swap method for r and s stereochemistry

Swap Method Trick for quickly finding R and S configurations when group #4 not forward/back. Save time AND forget your model kit and mental molecule manipulations redrawing structures on your exam.


Video 5 – R & S Configuration for Lengthy Complex Substituents

R and S configurations for complex chiral moleculesThis orgo tutorial video shows you how to approach lengthy and complex substituents so that you can quickly and easily determine R and S configurations.



Video 6 – Fischer Projection Stereochemistry TrickFischer Projection Stereochemistry Finding R and S configurations

This video shows you how to quickly and easily find R and S configurations directly on the Fischer Projection. Guaranteed to save you time on your next stereochemistry quiz/exam.

Video 7 – Newman Projection Stereochemistry R&S Trick

Newman projection stereochemistry r and s configuratios tutorial videoThis video teaches you how to quickly find configurations of molecules presented in a Newman Projection. Learn how to view the molecule and quickly assign priority WITHOUT the need to redraw into a sawhorse projection.



Additional Chirality Videos to Follow