Oxidation and Reduction Reactions in Organic Chemistry

oxidation reduction reactions cheat sheet previewOxidation and Reduction Reactions Organic Chemistry Video SeriesOxidation and reduction reactions will come up over and over in your organic chemistry course.

You may remember redox from general chemistry as the topic involving half-cells, batteries, and metals with changing oxidation numbers.

While the science hasn’t changed at the organic chemistry level, the molecules and overall presentation is very different.

Instead of studying circuits and moving electrons, you’re looking at reactions of hydrocarbons gaining or losing bonds to oxygen and hydrogen atoms.

This series breaks down the various oxidation and reduction reactions you’ll come across in your organic chemistry course.

Download my Orgo Redox cheat sheet to follow along and try the redox practice quiz

Oxidation and Reduction in Organic Chemistry Tutorial Video SeriesVideo 1 – Introduction to Oxidation and Reduction Reactions in Organic Chemistry

This video introduces the concept of redox at the organic chemistry level. Learn how to identify oxidation and reduction reactions by analyzing oxidation number, bonds/atoms gained and bonds/atoms lost.

Examples include redox of alkenes, alkynes, alcohols and more, as well as what to look out for when faced with an unfamiliar reagent.

Alkenes & Alkynes Oxidation Reduction and Oxidative Cleavage Leah FischVideo 2 – Oxidation & Reduction Alkenes and Alkynes

This video serves as a quick overview of oxidation/reduction reactions you’ve likely covered when studying alkenes and alkynes.

Specific focus on how to recognize Oxidation and Reduction based on reactants/product, how to identify reagents, and of course oxidative cleavage comparisons.

Birch Reduction Reaction and Mechanism Benzene and Substituted Rings Leah4sciVideo 3 – Birch Reduction Reaction and Mechanism

The Birch Reduction is an interesting reaction that appears to go against the desire for molecular stability. This reaction has the power to disrupt and aromatic compound such as benzene and turn it into a partially reduxed non-conjugated diene

 

Oxidation of Alcohols to Aldehyde Ketone and Carboxylic Acid Video by Leah4sciVideo 4 – Oxidation of Alcohols to Aldehyde Ketone and Carboxylic Acid

Oxidation of Alcohol products will vary based on the substitution of the starting alcohol and the specific oxidizing reagent used for the reaction.

Products will include Aldehydes, Ketones, or Carboxylic acids.

Alcohol Oxidation Mechanism with H2CrO4, PCC and KMnO4 tutorial by Leah4sci

Video 5 – Alcohol Oxidation Mechanism

The nature of alcohol oxidation depends greatly on the molecules reactivity and the nature of the oxidizing reagent.

This video walks you through the step by step mechanism for the common alcohol oxidation mechanisms. Chromic Acid, PCC, and KMnO4

Sodium Borohydride (NaBH4) Reduction Tutorial Video by Leah4sci

Video 6 – Sodium Borohydride (NaBH4) Reduction

You’ll cover a variety of reactions involving the reduction of carbonyl compounds.

NaBH4 is a weak reducing agent commonly seen reacting with ketones to form secondary alcohols and aldehydes to form primary alcohols.

This video will help you understand the nature of this reaction, sodium borohydride activity, and of course the step by step reaction mechanism.

Video 7 – Sodium Borohydride (NaBH4) vs Lithium Sodium Borohydride (NaBH4) vs Lithium Aluminum Hydride (LiAlH4) Tutorial Video by Leah FischAluminum Hydride (LiAlH4)

LiAlH4 is the stronger ‘hydride’ carbonyl reducing agent. In addition to reducing aldehydes and ketones, it’ll also reduce carboxylic acids and carboxyl derivatives.

This video takes you through the molecule, reaction, examples and step by step mechanism.

Lithium Aluminum Hydride (LiAlH4) Reduction Tutorial Video by Leah4sci

Video 8 – Lithium Aluminum Hydride (LiAlH4) Reduction

 

 

DiBAl-H Reduction Reaction of Ester or Nitrile to Aldehyde Tutorial Video by Leah4sci

Video 9 – DiBAl-H Reduction Reaction of Ester or Nitrile to Aldehyde

 

 

Clemmensen and Wolff Kishner Reduction of Ketones and Aldehydes Tutorial Video by Leah4sciVideo 10 – Clemmensen and Wolff Kishner Reduction of Ketones and Aldehydes

 

 

Aromatic Side Chain Oxidation to Carboxylic Acid by Leah4sci

Video 11 – Aromatic Side Chain Oxidation

 

 

 

Tollens Reagent Silver Mirror Test for Aldehydes by Leah4sci

 Video 12 – Tollens Reagent Silver Mirror Test for Aldehydes

 

 

 

Additional redox videos (Coming soon)

  • Aromatic Side Chain Reactions
  • Redox in Lab: Jones and Tollens
  • Oxidation/Reduction of Amines, Imines, and Nitriles

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