R and S Configuration using Cahn Ingold Prelog Priority Rules

R and S Configuration Cahn Ingold Prelog rules for ranking by Leah4sciChirality/Stereochemistry Video Series: Video 2
Chiral carbons are identified as having 4 unique substituents. Finding the Absolute Configuration – R and S comes as a result of ranking and order substituents, specifically by noting the configuration of the top 3 groups.

This video shows you how to prioritize substituents to find R and S configurations using the Cahn-Ingold-Prelog priority rules.

(Watch on YouTube: R/S. Click cc on bottom right for video transcription.)

<– Watch Previous Video: Introduction to Chirality and Stereochemistry
–> Watch Next Video: Finding R and S When Group #4 is Forward

This is Video 2 in the Chirality/Stereochemistry Video Series. Click HERE for the entire series.

Ready to test your stereochemistry skills? Try my FREE Chirality/Stereochemistry Practice Quiz and follow along with the Stereochemistry Cheat Sheet

Would a Model Kit help you? Watch How to Use Your Organic Chemistry Model Kit.


  1. benjamin oppong says

    simply educative

  2. kriishna karkee says

    it is helpful for me

  3. kriishna karkee says

    it is a helpful lesson .

  4. Thank you so much for your helpful videos. They are very informative!

  5. I will be glad to enroll in any school you teach

  6. Hi, I just wanted to say thank you for being a great instructor, your videos are really good, I’m waiting for video #3 on diasteromers and rotation, I’m having a hard time with rotation…Thank You!!!

  7. Thank you so much. I like the way you breakdown to identify R and S configurations.

  8. maliha ludin says

    Hi leah, when will you post the next video in this series? Thanks!

  9. Khushbu Ruman says

    Thank you so much! you are the best teacher!

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