R and S Configuration using Cahn Ingold Prelog Priority Rules

R and S Configuration Cahn Ingold Prelog rules for ranking by Leah4sciChirality/Stereochemistry Video Series: Video 2
Chiral carbons are identified as having 4 unique substituents. Finding the Absolute Configuration – R and S comes as a result of ranking and order substituents, specifically by noting the configuration of the top 3 groups.

This video shows you how to prioritize substituents to find R and S configurations using the Cahn-Ingold-Prelog priority rules.

(Watch on YouTube: R/S. Click cc on bottom right for video transcription.)

<– Watch Previous Video: Introduction to Chirality and Stereochemistry
–> Watch Next Video: Finding R and S When Group #4 is Forward

This is Video 2 in the Chirality/Stereochemistry Video Series. Click HERE for the entire series.

Ready to test your stereochemistry skills? Try my FREE Chirality/Stereochemistry Practice Quiz and follow along with the Stereochemistry Cheat Sheet

Would a Model Kit help you? Watch How to Use Your Organic Chemistry Model Kit.


  1. benjamin oppong says:

    simply educative

  2. kriishna karkee says:

    it is helpful for me

  3. kriishna karkee says:

    it is a helpful lesson .

  4. Thank you so much for your helpful videos. They are very informative!

  5. I will be glad to enroll in any school you teach

  6. Hi, I just wanted to say thank you for being a great instructor, your videos are really good, I’m waiting for video #3 on diasteromers and rotation, I’m having a hard time with rotation…Thank You!!!

  7. Thank you so much. I like the way you breakdown to identify R and S configurations.

  8. maliha ludin says:

    Hi leah, when will you post the next video in this series? Thanks!

  9. Khushbu Ruman says:

    Thank you so much! you are the best teacher!

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