SN1 Reaction Mechanism Examples of Unimolecular Substitution Part 2

SN1 SN2 E1 Series: Video 16 Unimolecular Nucleophilic Substitution video 2 of 3 – this video takes you through additional SN1 reaction mechanism examples. As you work through this video pay attention to the logic, concepts, and especially patterns. Doing so will help you understand when to choose SN1 while avoiding confusing memorization (Watch on […]

SN1 Reaction Rate and Mechanism – Unimolecular Nucleophilic Substitution Part 1

SN1 SN2 E1 Series: Video 9 This video is the first of 3 Unimolecular Nucleophilic Substitution reaction tutorials. This video breaks down the reaction, rate, and step by step mechanism for the SN1 reactions including a few simple examples to help you follow along. Pay special attention to the key identifyers of an SN1 reaction […]

Oxygen As A Leaving Group Using Tosylate And Mesylate in Substitution and Elimination Reactions

SN1 SN2 E1 Series: Video 8 Oxygen makes a poor leaving group in substitution and elimination reactions. That is, when left in its initial form. The key to kicking out an oxygen is to ‘bribe it’ by turning it into a better leaving group. Watch this video for a detailed explanation with examples using tosylate, […]

Leaving Groups in Substitution and Elimination Reactions Part 1

SN1 SN2 E1 Series: Video 7 When determining between substitution and elimination reactions, the final step in the 4-part checklist involves the leaving group. Can it leave?¬†Will it leave? (Watch on YouTube: Leaving Groups 1. Click CC on bottom right for transcript.) <– Watch Previous Video: Polar Protic, Aprotic, and Non-Polar Solvents in Substitution and […]

Alkyl Halide Carbon Chain Analysis for SN1 SN2 E1 E2 Reactions

SN1 SN2 E1 Series: Video 3 When determining between substitution and elimination reactions, the first and most important aspect to analyze is the alkyl chain. Understanding how the position of the leaving group impacts reactions will help you determine which reaction types are possible and which reactions to rule out. Watch this video for a […]

Nucleophile And Base Analysis Part 2

SN1 SN2 E1 Series: Video 5 Once you understand the similarities and differences between nucleophiles and bases, you need to understand how to differentiate the molecules that prefer to act as just one or the other. This video helps you understand strong bases that make weak ¬†nucleophiles and strong nucleophiles that are weak bases. (Watch […]

Polar Protic, Aprotic, and Non-Polar Solvents in Substitution and Elimination Reactions

SN1 SN2 E1 Series: Video 6 Solvents play a key role in SN1 SN2 E1 and E2 reactions. But instead of memorizing, I want you to understand what makes a solvent polar, and what makes a polar solvent protic or aprotic. By understanding how the solvent interacts with the¬†intermediates you’ll have an easier time predicting […]

Nucleophilicity vs Basicity in Substitution Elimination Reactions Part 1

SN1 SN2 E1 Series: Video 4 As an orgo tutor, one of the most common substitution/elimination questions I get relates to “What’s the difference between a nucleophile or base?” or “How can I tell a nucleophile from a base?” And the answer? They are THE SAME! Watch this video to understand the concept of Nucleophile […]

Introduction To Nucleophilic Substitution and Beta Elimination Reactions

SN1 SN2 E1 Series: Video 1 Nucleophilic Substitution and Beta Elimination reactions are potentially the most difficult as compared to your organic chemistry 1 course. Why is it so difficult? Unlike your alkene or alkyne reactions, when it comes to SN1 SN2 E1 E2 reactions you have to focus on concepts and mechanisms. You have […]