During synthesis, protecting a reactant is a game changer. Without this ability, arriving at the correct product will be painful and sometimes near impossible.

Utilizing a cyclic acetal protecting group is one of the handiest tools we can have in our synthesis arsenals.

This video will so you a step-by-step detailed mechanism along with tips for redrawing, and timesaving shortcuts! You can use these during your practice and upcoming exams.

(Watch on YouTube: Cyclic Acetal. Click CC for transcription.)

<– Watch Previous Video: Acetal and Hemiacetal Formation Reaction Mechanism
–> Test Yourself!: Acetal Practice Quiz

This is Video 3 in the Acetal Series. Click HERE for the entire series.

Test your understanding with the Acetal Practice Quiz!

Acetal and Hemiacetal mechanisms can be long, but when you UNDERSTAND each step you’ll be saved from a big headache and trouble from merely memorizing.

This video walks you step-by-step through the acid catalyzed acetal formation reaction mechanism!

You’ll see special attention on the acetal, hemiacetals, ketals, and hemiketals in the mechanism as well as resonance so you see exactly WHY each step is taking place. You’ll also see the pattern so you can apply this to more mechanisms!

(Watch on YouTube: Acetal Mechanism. Click CC for transcription.)

<– Watch Previous Video: Acetal Ketal Hemiacetal Hemiketal Reactions Overview & Shortcuts
–> Watch Next Video: Cyclic Acetal Protecting Group Reaction and Mechanism

Links & Resources Mentioned In This Video:

• Resonance Video Tutorial Series
• PKA Based on Logic
• Formal Charge Shortcut 

This is Video 2 in the Acetal Series. Click HERE for the entire series.

Test your understanding with the Acetal Practice Quiz!

This video offers an overview and comparison between the acetal, ketal, hemiacetal, and hemiketal reactions including stability of products and intermediates.

You’ll also learn my shortcut trick for quickly identifying carbonyl and alcohol reactants from products and acetal or ketal products from reactants.

(Watch on YouTube: Acetal Overview. Click CC for transcription.)

–> Watch Next Video: Mechanism for Acetal & Hemiacetal Formation in Acids and Bases

This is Video 1 in the Acetal Series. Click HERE for the entire series.

Test your understanding with the Acetal Practice Quiz!