Electrophilic Aromatic Substitution reactions are one of the more fun topics that you will study in Organic Chemistry. But perhaps you find it tricky due to the sheer volume of information that makes up the big picture. And so, in addition to my EAS Tutorial Video Series I’ve put together a thorough EAS cheat sheet. […]
Ortho Meta Para Directing Effects in EAS Reactions
Ortho, Meta and Para refer to the 1-2, 1-3, and 1-4 relationships between benzene substituents. In Electrophilic Aromatic Substitution reactions, O/M/P directing effects help us figure out where to place the incoming electrophile. Electron Donating Groups activate the ring for ortho and para addition. Electron Withdrawing Groups deactivate the ring for meta addition. Halogens are the one exception.
Halogen Exception Ortho Para Deactivators Tutorial Video
EAS Series: Video 13 This video shows you the unique directing effects of halogens on substituted benzene. Learn why they are ortho para directing yet still deactivate the benzene ring towards electrophilic aromatic substitution. (Watch on YouTube: Halogen Exception. Click CC on bottom right for transcript.) <– Watch Previous Video: Meta Direction Groups This is […]
Meta Direction Groups Video
EAS Series: Video 12 This video shows you the nature of deactivating groups as meta directors through through logic and structure to help you avoid memorization. (Watch on YouTube: M Directing. Click CC on bottom right for transcript.) <– Watch Previous Video: Ortho Para Directing Groups –> Watch Next Video: Halogen Exception Orgo Para Deactivators […]
Ortho Para Directing Groups Video
EAS Series: Video 11 This video takes you through the logic and structure of the ortho and para directing activating groups. (Watch on YouTube: O/P Directing. Click CC on bottom right for transcript.) <– Watch Previous Video: Resonance + Trick for Ortho Meta Para Additions EAS –> Watch Next Video: Meta Direction Groups This is […]
Resonance Trick Ortho Meta Para Addition EAS Intermediates
EAS Series: Video 10 Electrophilic Aromatic Substitution gets more difficult when the starting molecule is a substituted benzene. Not only do you have to know the reaction. You also have to know how the substituent will direct the incoming electrophile, and if the substituent will slow down (deactivate) or speed up (activate) the overall reaction. […]
Ortho Meta and Para Disubstituted Benzene Monster Trick Video
EAS Series: Video 9 This video shows my fun trick for easily recognizing ortho, meta, and para substituents on a disubstituted benzene. This will be extremely important once you start reacting substituted benzene. (Watch on YouTube: Trick. Click CC on bottom right for transcript.) <– Watch Previous Video: Friedel Crafts Alkylation vs Acylation EAS Reactions […]
Friedel Crafts Alkylation vs Acylation EAS Reactions Tutorial Video
EAS Series: Video 8 This video shows you a comparison of the Friedel-Crafts alkylation and acylation reactions, including the limitations of FC alkylation, and how to convert an acylation product to the reduced alkyl version. (Watch on YouTube: Alkylation v. Acylation. Click CC on bottom right for transcript.) <– Watch Previous Video: Friedel Crafts Acylation […]
Friedel Crafts Acylation EAS Reaction and Mechanism Video
EAS Series: Video 7 This video shows you the mechanism for the formation of acylium ion with a Lewis Acid catalyst to form the super electrophile that is attacked by benzene in the Friedel-Crafts Acylation reaction. (Watch on YouTube: Acylation. Click CC on bottom right for transcript.) <– Watch Previous Video: Friedel Crafts Alkylation EAS […]
Friedel Crafts Alkylation EAS Reaction and Mechanism Video
EAS Series: Video 6 This video shows you the mechanism for the formation of carbocation in a Lewis Acid as the super electrophile that is attacked by benzene in the Friedel-Crafts Alkylation reaction. This reaction produces an alkylated benzene. (Watch on YouTube: Alkylation. Click CC on bottom right for transcript.) <– Watch Previous Video: EAS […]
