During synthesis, protecting a reactant is a game changer. Without this ability, arriving at the correct product will be painful and sometimes near impossible. Utilizing a cyclic acetal protecting group is one of the handiest tools we can have in our synthesis arsenals. This video will so you a step-by-step detailed mechanism along with tips for redrawing, […]

Acetal and Hemiacetal mechanisms can be long, but when you UNDERSTAND each step you’ll be saved from a big headache and trouble from merely memorizing. This video walks you step-by-step through the acid catalyzed acetal formation reaction mechanism! You’ll see special attention on the acetal, hemiacetals, ketals, and hemiketals in the mechanism as well as […]

This video offers an overview and comparison between the acetal, ketal, hemiacetal, and hemiketal reactions including stability of products and intermediates. You’ll also learn my shortcut trick for quickly identifying carbonyl and alcohol reactants from products and acetal or ketal products from reactants.   (Watch on YouTube: Acetal Overview. Click CC for transcription.) –> Watch […]