Chirality/Stereochemistry Video Series: Video 4
R and S configurations are pretty straight-forward when priority group #4 is conveniently in the back of the molecule. There's even a quick trick for when group #4 is forward (as taught in this video).
But what happens when priority group #4 is in the plain of the page? Do you treat it as a rear group, forward group?
Many professors will teach you to build a model kit (hint: don't rely on your model kit) or mentally rotate and redraw the molecule placing group #4 in the back
OUCH! Not only are these methods a waste of time, they introduce too much stress and confusion on exams. My swap method taught below is tricky to learn at first. BUT… once you get it I GUARANTEE you'll find yourself saving 5, 10, even 15 minutes on your stereochemistry exam questions.
(Watch on YouTube: Swap. Click cc on bottom right for video transcription.)
I have been watching your videos for a while now but this is the first time that I didn’t get word of what you are saying
You’re my favorite online tutor, hands down! Thank you for explaining things so clearly and teachings us your little hacks, it really helps 🙂
I would like to say THANK YOU to you for making these amazing videos. Honestly, I learn so much from your explanations in each video than I do in my Organic Chemistry class. Hands down. I am so ever glad I stumbled on these videos. Thanks again.
Sincerely,
Tu Anh Nguyen
Your meathodology is the best for organic chemistry thanks
Vert helpful thank you very much
How do you know how many swaps to perform? Enantiomers Vs. Same compound
nice one please add some more for neet
Couldn’t we just flip R to S and vice versa after one swap!?
woooow! Just woooow! I wish you were my teacher I swear, you are a very awesome person………………….. please keep on doing this okayyy!
I have just watched your videos and they are amazing.how can I download the organic chem 2 book that you recommend in one of your videos
Your videos are very helpful. Plz make video on Meso compounds also.
Thanks Komal. I have plans to add that video in the coming year
Amazing! A great help to me !
You’re very welcome Devdatta
THANK YOU! 🙂
U r awesome at teaching R and S
Why don’t you just swap once and reverse the chirality…
why is it necassary in this theory that it always work only when substituent 4 is behind(back)of the steriogenic centre(if u cn explain me with context to ur model in vedio it wld be awesome to get a feel of chem)?