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Chirality and Stereochemistry Practice Quiz

August 28, 2022 By Leah4sci 78 Comments

Chirality and Stereochemistry R S Enantiomers Diastereomers Meso Tutorial Series

The key to mastering chirality and stereochemistry is through practice, practice, and more practice. But where do you get all those practice problems? After reviewing the videos in my Chirality and Stereochemistry series, and working through the simple questions in each, see how well you’ve mastered the material by trying my Stereochemistry Practice Quiz below. The […]

Filed Under: Organic Chemistry Practice Problems Tagged With: chirality, enantiomers, orgo quiz, quiz, r and s, stereochemistry

Chirality and Stereochemistry Cheat Sheet Study Guide

February 4, 2020 By Leah4sci 26 Comments

Chirality Stereochemistry Cheat Sheet Study Guide Preview

Chirality is a tough organic chemistry topic. But if you’re reading this you already know. Be sure to watch my chirality video series to make sense of chiral atoms, enantiomers, absolute configuration and finding R/S for simple and complex molecules. The cheat sheet below is meant to serve as a study guide to help you as […]

Filed Under: Organic Chemistry Reference Material Tagged With: chirality, diastereomers, enantiomers, meso, stereochemistry

Enantiomeric Excess Percent Optical Purity Calculations and Logic

October 19, 2017 By Leah4sci 7 Comments

Enantiomeric Excess Percent Optical Purity in Series by Leah4sci

Enantiomeric excess percentage (aka optical purity percentage) calculations are one of the few equations you’ll come across in your orgo course. This video gives you a  step by step breakdown and practice examples. You’ll see how to find the percent excess via logic and see the numbers side by side. (Watch on YouTube: Optics 3. Click […]

Filed Under: Chirality and Stereochemistry Tagged With: chirality, optical activity, stereochemistry

Stereochemistry of Amino Acids RS to DL

March 13, 2016 By Leah4sci 1 Comment

Amino Acid Stereochemistry RS DL

Amino acids are biologically active molecules. 19 of the 20 common amino acids have a chiral alpha carbon, 2 amino acids (Leucine and Threonine) have a second chiral center in their side chain. This video shows you how to Find R/S for 3-D amino acids Find R/S and D/L for amino acid Fischer projections Trick […]

Filed Under: Amino Acids Tagged With: amino acids, chirality, fischer projection, stereochemistry

Specific Rotation Calculation in Optical Activity

February 23, 2018 By Leah4sci 1 Comment

Specific Rotation in Optical Activity in Chirality & Stereochemistry Video Tutorial Series by Leah4sci

Specific Rotation calculations are a useful tool in optical activity. This video will help you understand the factors influencing specific rotation such as observed rotation, g/mL, path-length, wavelength, and temperature. You will see a detailed breakdown of the equation along with a few examples to follow along. (Watch on YouTube: Optics 2. Click CC for video transcription.) <– […]

Filed Under: Chirality and Stereochemistry Tagged With: chirality, optical activity, stereochemistry

Polarimetry in Optical Activity

October 18, 2017 By Leah4sci 1 Comment

Polarimetry Optical Activity in Chirality and Stereochemistry by Leah4sci

Polarimetry is the key to understanding chiral molecules in terms of optical activity. This video goes behind the scenes of the polarimeter to help you understand what plane polarized light has to do with chiral molecules. Part 1 (of 3) in this mini series explains + D and – L, dextrorotatory and levorotatory, and their (lack […]

Filed Under: Chirality and Stereochemistry Tagged With: chirality, optical activity, stereochemistry

Newman Projection Stereochemistry R & S Trick

December 15, 2015 By Leah4sci 10 Comments

Newman projection stereochemistry r and s configuratios tutorial video

Chirality/Stereochemistry Video Series: Video 7 Finding R and S configurations for non-traditional molecules can be somewhat tricky. This video teaches you how to quickly find configurations of molecules presented in a Newman Projection. Learn how to view the molecule and quickly assign priority WITHOUT the need to redraw into a sawhorse projection. (Watch on YouTube: […]

Filed Under: Chirality and Stereochemistry Tagged With: chirality, newman projection, stereochemistry

Fischer Projection R and S Stereochemistry Trick

December 15, 2015 By Leah4sci 24 Comments

Fischer Projection Stereochemistry Finding R and S configurations

Chirality/Stereochemistry Video Series: Video 6 Fischer projections provide a simple 2-dimensional representation for complex 3-dimensional structures. Which is great for drawing complex molecules, but not so much fun if asked to determine R and S configurations. Many books and professors will have you redraw the Fischer projection into a 3-dimensional sawhorse or skeletal structure. I […]

Filed Under: Chirality and Stereochemistry Tagged With: chirality, diastereomers, fischer projection, stereochemistry

R and S configuration for Lengthy Complex Substituents

December 15, 2015 By Leah4sci 15 Comments

R and S configurations for complex chiral molecules

Chirality/Stereochemistry Video Series: Video 5 R and S configurations are found by ranking substituents on a chiral carbon. This is relatively straight-forward when substituents contain 1-3 atoms. This gets more confusing when the substituents are long, complex, and contain many of the same atoms. This orgo tutorial video shows you how to approach lengthy and […]

Filed Under: Chirality and Stereochemistry Tagged With: cahn ingold prelog, chirality, stereochemistry

Swap Method for finding R and S Configurations Chirality

December 16, 2016 By Leah4sci 18 Comments

swap method for r and s stereochemistry

Chirality/Stereochemistry Video Series: Video 4 R and S configurations are pretty straight-forward when priority group #4 is conveniently in the back of the molecule. There’s even a quick trick for when group #4 is forward (as taught in this video). But what happens when priority group #4 is in the plain of the page? Do […]

Filed Under: Chirality and Stereochemistry Tagged With: chirality, r and s, stereochemistry, swap method

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