Strecker Synthesis of Amino Acids

Strecker Synthesis is one of the first laboratory methods for synthesizing an alpha amino acid.

Strecker synthesis starts out with a nucleophilic addition of nitrogen to an aldehyde followed by a SECOND nucleophilic addition of cyanide (nitrile group) to the imine intermediate.

This video walks you through the overall reaction followed by a step by step breakdown of the Strecker reaction and mechanism.

(Watch on YouTube: Strecker Synthesis. Click cc on the bottom right for video transcript)

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This is video 8 in the Amino Acids Series. Click for complete series + Practice Quiz and Cheat Sheet

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