Organic Chemistry Tutorial Videos

Acetal Reactions Practice Quiz

Acetal Practice Quiz by Leah4sci

The quiz below requires some mastery in reactions, intermediates, and step-by-step mechanisms. Not ready? Start by gaining your foundation in the Acetal Tutorial Video Series! Scroll to the very bottom of this quiz for a link to the FREE quiz solutions PDF (Coming Soon!) to ensure you’ve got this down. This session will be solved LIVE (This […]

Acetal Ketal Hemiacetal Hemiketal Reactions Overview and Shortcuts

Acetals Ketals Hemiacetals Hemiketals Overview in Organic Chemistry

This video offers an overview and comparison between the acetal, ketal, hemiacetal, and hemiketal reactions including stability of products and intermediates. You’ll also learn my shortcut trick for quickly identifying carbonyl and alcohol reactants from products and acetal or ketal products from reactants.   (Watch on YouTube: Acetal Overview. Click CC for video transcription.) –> […]

Specific Rotation Calculation in Optical Activity

Specific Rotation in Optical Activity in Chirality & Stereochemistry Video Tutorial Series by Leah4sci

Specific Rotation calculations are a useful tool in optical activity. This video will help you understand the factors influencing specific rotation such as observed rotation, g/mL, path-length, wavelength, and temperature. You will see a detailed breakdown of the equation along with a few examples to follow along. (Watch on YouTube: Optics 2. Click CC for video transcription.) <– […]

Physical Properties of Alcohol: Hydrogen Bonding, Solubility, and Boiling Point

Physical Properties of Alcohol Solubility and Boiling Point Video Tutorial in Organic Chemistry by Leah Fisch

The key to understanding physical properties of alcohol, including hydrogen bonding solubility and boiling point is to understand the structure and charge distribution within the alcohol functional group. This video will show you the behind-the-scenes intermolecular forces at work that affect alcohol’s ability to hydrogen bond for solubility in water, miscibility, and boiling point trends. You’ll […]

Introduction to Alcohol Reactions

Introduction to Alcohol Reactions by Leah Fisch

The key to mastering alcohol reactions is understanding WHY they react as they do. What about the OH functional group makes it want to attack or get attacked, as you will learn in later mechanisms? This video will give you a solid foundation to help you prepare to master the more advanced reactions starting with […]

Enantiomeric Excess Percent Optical Purity Calculations and Logic

Enantiomeric Excess Percent Optical Purity in Series by Leah4sci

Enantiomeric excess percentage (aka optical purity percentage) calculations are one of the few equations you’ll come across in your orgo course. This video gives you a  step by step breakdown and practice examples. You’ll see how to find the percent excess via logic and see the numbers side by side. (Watch on YouTube: Optics 3. Click […]

Polarimetry in Optical Activity

Polarimetry Optical Activity in Chirality and Stereochemistry by Leah4sci

Polarimetry is the key to understanding chiral molecules in terms of optical activity. This video goes behind the scenes of the polarimeter to help you understand what plane polarized light has to do with chiral molecules. Part 1 (of 3) in this mini series explains + D and – L, dextrorotatory and levorotatory, and their (lack […]

Swap Method for finding R and S Configurations Chirality

swap method for r and s stereochemistry

Chirality/Stereochemistry Video Series: Video 4 R and S configurations are pretty straight-forward when priority group #4 is conveniently in the back of the molecule. There’s even a quick trick for when group #4 is forward (as taught in this video). But what happens when priority group #4 is in the plain of the page? Do […]

Friedel Crafts Alkylation vs Acylation EAS Reactions Tutorial Video

alkylation vs acylation by Leah4sci

EAS Series: Video 8 This video shows you a comparison of the Friedel-Crafts alkylation and acylation reactions, including the limitations of FC alkylation, and how to convert an acylation product to the reduced alkyl version. (Watch on YouTube: Alkylation v. Acylation. Click CC on bottom right for transcript.) <– Watch Previous Video: Friedel Crafts Acylation […]

Choosing SN1 SN2 E1 E2 Reaction Mechanism


This video provides a step by step walk through of a difficult SN1 SN2 E1 E2 mechanism when given a product. This question comes from a student’s practice exam where over 100 students failed to get full credit. You can learn how to ace questions like this by paying attention to the LOGIC more than just […]